Lonesome George was the famed last representative of a giant tortoise species once found on the Galapagos island of Pinta. Image credit: Mark Putney

Famous giant tortoise DNA may hold fountain of youth: UCBO

After Lonesome George’s death he still provides clues to longer life

Ever since Darwin’s first steps on the Galapagos Islands, understanding the adaptations that offer the giant tortoise its extended lifespan has been a tantalizing scientific pursuit.

And now, new research by an international team including researchers from UBC’s Okanagan campus has used the DNA from one famous giant tortoise to uncover the genes that are associated with their longevity. The discovery provides clues to better understand aging in humans and may help preserve the species says Michael Russello, study co-author and biology professor at UBC Okanagan.

“Giant tortoises are among the longest living vertebrate animals and have become an interesting model for studying longevity and age related-disease,” said Russello. “Even though they’re one of few animals that can live longer than 100 years, there has been surprisingly little research into the giant tortoise genome.”

RELATED: UBCO and BCIT team up to brew cannabis-infused beverages

To help identify the genes that give the giant tortoise its extended lifespan, the researchers compared the complete DNA sequence from two long-lived giant tortoises. They used samples from Lonesome George—the famed last representative of a species once found on the Galapagos island of Pinta—and from another giant tortoise species found on the Aldabra atoll, a coral island in the Indian Ocean.

RELATED: UBCO sociology class calls on Kelowna Chiefs to change “derogatory” name

By comparing the giant tortoise genomes with those from other species, including humans, they found interesting variation within genes linked to DNA repair, immune response, and cancer suppression not possessed by shorter-lived vertebrates. None of those genomic variants had been previously associated with aging, offering new avenues for further study.

While individual tortoises have remarkable longevity, Russello says the Galapagos giant tortoises do not, with all living species considered threatened or endangered. He says the results of their study could provide clues into the biological processes and adaptations that gave rise to giant tortoises in the first place, while helping to better protect these animals on the verge of disappearing altogether.

“Lonesome George was a very interesting character in his own right, embodying the plight of endangered species until his death in 2012,” said Russello. “While he inspired many while he was alive, his legacy now lives on through a story written in his DNA.”

To report a typo, email:
newstips@kelownacapnews.com
.


@KelownaCapNews
newstips@kelownacapnews.com

Like us on Facebook and follow us on Twitter.

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

VALLEY SENIORS: A second chance comes with enough memories for two

The Dietrich family makes its mark on Abbeyfield House in Port Alberni

Inquest into death of Jocelyn George postponed due to COVID-19

Coroner’s inquest into 2016 death of Port Alberni woman was supposed to start July 6

Port Alberni’s Joe Hill celebrates 90th birthday with waves through a window

Retired accountant receives best wishes via Zoom, meets newborn great-grandchild

Alberni Golf Club reopens with new COVID-19 rules

J and L Mixed Scramble kicks off 2020 season

Help is available for Port Alberni businesses restarting after COVID-19 closures

Popular food truck finds a new location on Johnston Road

Minimum wage goes up June 1 in B.C. as businesses face COVID-19 challenges

The minimum wage jumps by 75 cents to $14.60 an hour on Monday

An ongoing updated list of Alberni Valley events affected by COVID-19

Has your event been cancelled or postponed? Check here

Man dies in ATV accident south of Nanaimo

Incident happened on backroad Friday night in Nanaimo Lakes area

Protesters rally against anti-black, Indigenous racism in Toronto

Police estimated the crowd to be between 3,500 and 4,000 and said there was no violence

Feds earmark $1.5M to support recovery of B.C., Indigenous tourism

B.C. money will be split between Vancouver Island and Indigenous tourism

‘We’re sick of it’: Anger over police killings shatters U.S.

Tens of thousands marched to protest the death of George Floyd

Surrey mayor’s party under fire for ‘sickening’ tweet accusing northern B.C. RCMP of murder

Mayor Doug McCallum says tweet, Facebook post ‘sent out by unauthorized person’

Father’s Day Walk Run for prostate cancer will be virtual event this year throughout B.C.

The annual fundraiser for Prostate Cancer Foundation BC has brought in $2.5 million since 1999

Dr. Bonnie Henry announces official ban on overnight kids’ camps this summer

New ban comes after talking with other provincial health officials across the country, Henry says

Most Read